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Allele : Gt(ROSA)26Sor<tm2(CAG-GFPT1*G451E)Xen> gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Taconic Biosciences
Primary Identifier  MGI:7530916 Allele Type  Targeted
Attribute String  Conditional ready, Humanized sequence, Inserted expressed sequence Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct consisting of an F3 site, a neomycin resistance cassette, CAG promoter, loxP-flanked transcriptional termination cassette, FLAG-HA tagged human GFAT1 open reading frame containing a glycine to glutamate substitution at residue 451, human growth hormone polyadenylation signal and additional polyadenylation signal and FRT site were inserted into the locus. Upon cre-mediated recombination, the STOP cassette can be removed to get expression of the mutant human GFAT1 under the control of the CAG promoter.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • huGFAT1 G451E OE,
  • huGFAT1 G451E OE
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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