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Allele : Tg(Pcp2-ATXN3*69Q)1Hirai transgene insertion 1, Hirokazu Hirai

Primary Identifier  MGI:7513806 Allele Type  Transgenic
Attribute String  Epitope tag, Inserted expressed sequence Gene  Tg(Pcp2-ATXN3*69Q)1Hirai
Strain of Origin  C57BL/6NCrSlc Is Recombinase  false
Is Wild Type  false
molecularNote  The cDNA encoding a N-terminal-truncated form (lacking 286 amino-acid residues) of human ATAXIN-3 with 69 glutamine repeats is driven by a Purkinje-cell specific L7 promoter (Pcp2). The ATG start codon in exon 2 of Pcp2 was mutated to inhibit the expression of exons 1-3. In addition an N-terminal hemagglutinin epitope was added.
  • mutations:
  • Insertion
  • synonyms:
  • Tg(Pcp2-HA/ATXN3*69Q)1Hirai,
  • Tg(Pcp2-HA/ATXN3*69Q)1Hirai
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

1 Driven By

Trail: Allele

2 Publication categories

Trail: Allele