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Allele : Cdkn2a<em1(flpo,HBEGF/mCherry)Jpmb> cyclin dependent kinase inhibitor 2A; endonuclease-mediated mutation 1, Juan Pedro Martinez-Barbera

Primary Identifier  MGI:7514135 Allele Type  Endonuclease-mediated
Attribute String  Inserted expressed sequence, Recombinase, Reporter Gene  Cdkn2a
Transmission  Germline Strain of Origin  129S/SvEv-Gpi1<c>
Is Recombinase  true Is Wild Type  false
molecularNote  Using CRISPR/Cas9 system, a bicistronic targeting vector containing a mammalian optimized flippase (FLP) recombinase along with a diphtheria toxin receptor (HBEGF) fused with a mCherry fluorescent reporter separated by P2A sequences was inserted after the Stop codon in the exon3 of the Cdkn2a in ES cells.
  • mutations:
  • Insertion
  • synonyms:
  • p16-FDR,
  • p16-FDR
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

Trail: Allele

3 Publication categories

Trail: Allele