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Allele : Ilk<tm1.1Zentr> integrin linked kinase; targeted mutation 1.1, Roy Zent
Primary Identifier  MGI:7513913 Allele Type  Targeted
Gene  Ilk Transmission  Germline
Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  Glutamic acid codon 359 (GAA) in exon 11 was changed to lysine (AAA) (p.E359K) and a loxP site flanked neomycin resistance gene cassette was inserted into the 3' UTR in exon 13. The neo cassette was removed through subsequent Cre-mediated recombination. This mutation negatively affects the stability of the encoded peptide.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • E359K-ILK,
  • E359K-ILK
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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3 Publication categories

Trail: Allele




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