| Primary Identifier | MGI:7524752 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Kcnma1 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | An A to G change resulting in an aspartate to glycine substitution at amino acid 434 (p.D434G) was introduced in exon 10 and a loxP-flanked neomycin selection cassette was inserted downstream of the mutated exon 10. The neomycin selection cassette was removed via flp-mediated recombination. This is a variant identified in a large family of patients with generalized epilepsy and/or paroxysmal nonkinesigenic dyskinesia. |
