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Allele : Svep1<em1Nost> sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1; endonuclease-mediated mutation 1, Nathan O Stitziel

Primary Identifier  MGI:7516157 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Svep1
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  Aspartic acid codon 2699 (GAT) in exon 38 was changed to glycine (GGT) (p.D2699G) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutation is the equivalent of the human p.D2702G mutation associated with coronary artery disease (CAD).
  • mutations:
  • Single point mutation
  • synonyms:
  • Svep1<2699G>,
  • Svep1<2699G>,
  • Svep<G>,
  • Svep<G>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele