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Allele : Hnf1a<em1Jmer> HNF1 homeobox A; endonuclease-mediated mutation 1, Juanita L Merchant
Primary Identifier  MGI:7517040 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Hnf1a
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated an alanine to valine substitution at amino acid 98 (p.A98V). This missense mutation within the proximal DNA binding domain was identified in early-onset colorectal cancer patients.
  • mutations:
  • Single point mutation
  • synonyms:
  • HNF1A<A98V>,
  • HNF1A<A98V>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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