| Primary Identifier | MGI:7543153 | Allele Type | Endonuclease-mediated |
| Attribute String | Constitutively active | Gene | Slc26a5 |
| Strain of Origin | FVB/NJ | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Serine codon 396 (TCC) in exon 11 was changed to aspartic acid (GAC) (p.S396D) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutation renders the encoded peptide constitutively active, mimicking the chloride-bound state. |
