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Allele : Hand2<em1(dre)Pjen> heart and neural crest derivatives expressed 2; endonuclease-mediated mutation 1, Patricia Jensen
Primary Identifier  MGI:7543292 Allele Type  Endonuclease-mediated
Attribute String  Recombinase Gene  Hand2
Transmission  Germline Strain of Origin  (129S6/SvEvTac x C57BL/6NCrl)F1
Is Recombinase  true Is Wild Type  false
molecularNote  A 2A peptide, codon-optimized Dre (DreO) recombinase cDNA and SV40 poly(A) cassette were targeted to exon 2 of Hand2 by Crispr/Cas9 genome editing. Homologous recombination resulted in replacement of the Hand2 stop codon and 73 bp of 3' UTR with the 2A/Dreo/polyA cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Hand2Dre,
  • Hand2Dre
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0 Expresses

0 Mutation Involves

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Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Driven By

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