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Allele : Tg(Prnp-CHCHD2)U144Jaaw transgene insertion U144, Jung-A A Woo

Primary Identifier  MGI:7532878 Allele Type  Transgenic
Attribute String  Epitope tag, Inserted expressed sequence Gene  Tg(Prnp-CHCHD2)U144Jaaw
Is Recombinase  false Is Wild Type  false
molecularNote  The transgene insert contains the murine prion protein promoter and FLAG tag sequence in-frame with human CHCHD2 cDNA with a mutation that changes threonine codon 61(ACC) to isoleucine (ATC) (c.182C>T p.T61I). The mutation is found in some autosomal dominant Parkinson's disease (PD) patients.
  • mutations:
  • Insertion
  • synonyms:
  • CHCHD2-T61I<U144>,
  • CHCHD2-T61I<U144>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele