Primary Identifier | MGI:7532878 | Allele Type | Transgenic |
Attribute String | Epitope tag, Inserted expressed sequence | Gene | Tg(Prnp-CHCHD2)U144Jaaw |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The transgene insert contains the murine prion protein promoter and FLAG tag sequence in-frame with human CHCHD2 cDNA with a mutation that changes threonine codon 61(ACC) to isoleucine (ATC) (c.182C>T p.T61I). The mutation is found in some autosomal dominant Parkinson's disease (PD) patients. |