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Allele : Lrp8<tm1.1Dyh> low density lipoprotein receptor-related protein 8, apolipoprotein e receptor; targeted mutation 1.1, David Y. Hui

Primary Identifier  MGI:7537059 Allele Type  Targeted
Attribute String  Conditional ready Gene  Lrp8
Transmission  Germline Strain of Origin  129S/SvEv
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting construct was generated in which exons 1 and 2 was flanked with loxP sites placed 2.6 kb upstream of exon 1 in the 5’ UTR and 2.6 kb downstream of exon 2 within intron 2. For selection, a neomycin (Neo) cassette flanked by frt recombination sites was also inserted into intron 2. FLP-mediated recombination in the germline removed the neomycin cassette.
  • mutations:
  • Insertion
  • synonyms:
  • ApoER2<fl>,
  • ApoER2<fl>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele