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Allele : Slc38a9<em1(IMPC)J> solute carrier family 38, member 9; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:7537145 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Slc38a9
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GTAATAGTCAAGAGTCTCAC and GCCAGCAGGAGCTTAAGTTA, which resulted in a 1350 bp deletion beginning at Chromosome 13 position 112,689,111 bp and ending after 112,690,460 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000408687, ENSMUSE00000378819, ENSMUSE00000338903 (exons 4,5,6) and 1070 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 81 and early truncation 37 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele