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Allele : Lhx4<tm1.3Gan> LIM homeobox protein 4; targeted mutation 1.1, Lin Gan

Primary Identifier  MGI:7532845 Allele Type  Targeted
Attribute String  Null/knockout Gene  Lhx4
Transmission  Germline Strain of Origin  C57BL/6J x 129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting vector was constructed containing a floxed exon 3 of the Lhx4 gene, an FRT-flanked En2 splicing acceptor-IRES-tdTomatopGK-Neo (tdT-Neo) cassette into the intron upstream of the exon 3 of the Lhx4. FRT-flanked En2 splicing acceptor-IRES-tdTomatopGK-Neo (tdT-Neo) cassette was removed by FLPe recombinase leaving loxP flanked exon 3. The loxP flanked exon 3 was then removed by cre recombinase removing Exon 3 and resulting in a frameshift. This is a null allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Lhx4<->,
  • Lhx4<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele