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Allele : Gt(ROSA)26Sor<em2(CAG-PACS1)Gath> gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 2, Gary Thomas
Primary Identifier  MGI:7518817 Allele Type  Endonuclease-mediated
Attribute String  Conditional ready, Epitope tag, Humanized sequence, Inserted expressed sequence Gene  Gt(ROSA)26Sor
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/cas9 endonuclease-mediated genome editing is used to insert hemagluttin-tagged human PACS1 cDNA, followed by an IRES and a GFP reporter under the control of the widespread CAG promoter into the Gt(ROSA)26Sor locus. A loxP-flanked neomycin STOP precedes the PACS1 sequence. The GFP is too low to be detected and was only used for PCR genotyping.
  • mutations:
  • Insertion
  • synonyms:
  • ROSA2-LSL-PACS1-WT,
  • ROSA2-LSL-PACS1-WT,
  • Gt(ROSA)26Sor<tm1(CAG-LSL-Pacs1)Gath>,
  • R26<P1>,
  • Gt(ROSA)26Sor<tm1(CAG-LSL-Pacs1)Gath>,
  • R26<P1>
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