| Primary Identifier | MGI:7518961 | Allele Type | Endonuclease-mediated |
| Gene | Vax1 | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | CRISPR/Cas9 technology generated a lysine to alanine substitution at amino acid 101 and an arginine to alanine substitution at amino acid 102 (KR to AA) in exon 2. This AA mutation disrupts the GAG sugar-binding motif of Vax1 and generates an intercellular transfer (from optic stalk cells to retinal ganglion cell axons)-defective protein . |
