| Primary Identifier | MGI:7565616 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Ids |
| Strain of Origin | (C57BL/6 x DBA/2)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Proline codon 88 (CCA) in exon 3 was changed to leucine (CTA) (c.C263T, p.P88L) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutation is the equivalent of the human p.P86L (c.C257T) mutation associated with mucopolysaccharidosis type II (MPS II). |
