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Allele : Traf6<tm1.1Pcoh> TNF receptor-associated factor 6; targeted mutation 1.1, Philip Cohen
Primary Identifier  MGI:7620319 Allele Type  Targeted
Gene  Traf6 Transmission  Germline
Strain of Origin  C57BL/6NTac Is Recombinase  false
Is Wild Type  false
molecularNote  Leucine codon 74 (TTG) in exon 3 was changed to histidine (p.L74H) and an FRT site flanked puromycin resistance gene cassette was inserted into intron 2. The puro cassette was removed through subsequent Flp-mediated recombination. The mutation renders the encoded peptide catalytically inactive.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • TRAF6[L74H],
  • TRAF6[L74H]
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

4 Publication categories

Trail: Allele




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