| Primary Identifier | MGI:7628311 | Allele Type | Endonuclease-mediated |
| Gene | Mdm2 | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Serine codon 183 (TCC) in exon 9 was changed to alanine (GCC) (p.S183A) using an sgRNA (equivalent to GATCAAAGGACAGGGACCTGCGG) and an ssODN template with CRISPR/Cas9 technology. The mutation prevents phosphorylation of the residue in the encoded peptide. |
