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Allele : Grk1<tm1.1Elrw> G protein-coupled receptor kinase 1; targeted mutation 1.1, Ellen R Weiss

Primary Identifier  MGI:7550399 Allele Type  Targeted
Gene  Grk1 Transmission  Germline
Strain of Origin  C57BL/6NTac Is Recombinase  false
Is Wild Type  false
molecularNote  Serine codon 21 (AGT) in exon 1 was changed to alanine (p.S21A) and a loxP site flanked neomycin resistance gene cassette was inserted into intron 1. The neo cassette was removed through subsequent Cre-mediated recombination. The mutation prevents phosphorylation of the affected residue in the encoded peptide.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • GRK1-Ser21A,
  • GRK1-Ser21A
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele