| Primary Identifier | MGI:7628727 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Slc39a8 |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Alanine codon 393 (GCT) in exon 8 was changed to threonine (ACT) (p.A393T) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutation is the equivalent of the human p.A391T mutation (SNP rs13107325) associated with increased risk of schizophrenia, Crohnâs disease, obesity, dyslipidemia, and scoliosis. |
