| Primary Identifier | MGI:7562023 | Allele Type | Targeted |
| Gene | Zc3h12a | Transmission | Germline |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Serine codons 435 (TCA) and 439 (TCC) in exon 6 were changed to alanine (GCA, GCC) (p.S435A, p.S439A) and a loxP site flanked neomycin resistance gene cassette was inserted into intron 5. The neo cassette was removed through subsequent Cre-mediated recombination. The mutations block phosphorylation of the affected residues in the encoded peptide. |
