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Allele : Tfeb<em1Xinli> transcription factor EB; endonuclease-mediated mutation 1, Xinjian Li

Primary Identifier  MGI:7572842 Allele Type  Endonuclease-mediated
Gene  Tfeb Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  Cysteine codon 270 (TGC) in exon 4 was changed to serine (AGC) (p.C270S) using an sgRNA (targeting GCTTCTGAGTCAGGTCGGCA) and an ssODN template with CRISPR/Cas9 technology. The mutation blocks alkylation of the residue in the encoded peptide.
  • mutations:
  • Single point mutation
  • synonyms:
  • TFEB C270S,
  • TFEB C270S
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele