| Primary Identifier | MGI:7576151 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Htt |
| Strain of Origin | C57BL/6NTac | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The allele was generated using CRISPR/Cas9 endonuclease-mediated genome editing. The targeting vector was designed to replace the mouse huntingtin (Htt) intron 49, on chromosome 5, with a human HTT intron 49 sequence, which contained a putative splicing site to produce an alternative exon (iExon 49). This is Line7. |
