| Primary Identifier | MGI:7578878 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Ephb4 |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Phenylalanine codon 867 (TTT) in exon 15 was changed to leucine (CTT) (p.F867L) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutation is the equivalent of the same human mutation associated with vein of Galen malformations (VOGMs). |
