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Allele : Slc1a2<tm1.1Datr> solute carrier family 1 (glial high affinity glutamate transporter), member 2; targeted mutation 1.1, Davide Trotti
Primary Identifier  MGI:7620426 Allele Type  Targeted
Gene  Slc1a2 Transmission  Germline
Strain of Origin  C57BL/6NTac Is Recombinase  false
Is Wild Type  false
molecularNote  Aspartic acid codon 504 (GAC) in exon 10 was changed to asparagine (AAC) (p.D504N) and an FRT site flanked neomycin resistance gene cassette was inserted into intron 10. The neo cassette was removed through subsequent Flp-mediated recombination. The mutation renders the encoded peptide resistant to cleavage by caspase 3.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • EAAT2<CR>,
  • EAAT2<CR>,
  • EAAT2-D504N,
  • EAAT2-D504N
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele




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