| Primary Identifier | MGI:7639718 | Allele Type | Targeted |
| Gene | Cdh2 | Transmission | Germline |
| Strain of Origin | B6.Cg-Thy1<a> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Arginine codon (AGG) in exon 13 was changed to glycine (GGG) (p.R714G) and isoleucine codon (ATC) was changed to aspartic acid (GAT) (p.I715D). A loxP site flanked neomycin resistance gene cassette was inserted into intron 13 and subsequently removed through Cre-mediated recombination. The mutations renders the encoded peptide resistant to proteolytic cleavage by Adam10. |
