| Primary Identifier | MGI:7581062 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Espnl |
| Strain of Origin | Not Specified | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/Cas9 genome editing technology was used to create a deletion spanning from exon 1 to exon 8. This allele (c.135_1301del1165) forms protein p.A46Tfs14 and is referred to as Espnldelta. No labeling with BG35961 anti-ESPNL antibody was detected in cochlear hair bundles of homozygous mutant mice, indicating that this is a null allele. |
