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Allele : Myo3b<tm1Pgg> myosin IIIB; targeted mutation 1, Peter G Gillespie

Primary Identifier  MGI:7581078 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Myo3b
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  Conventional gene targeting eliminated exons 3 and 4, replacing them with a neomycin-resistance gene cassette conjugated to LacZ. A premature stop codon was introduced in exon 5. RT-PCR analysis of inner-ear mRNA demonstrated the expected truncated band in homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Myo3b<->,
  • Myo3b<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele