| Primary Identifier | MGI:7612311 | Allele Type | Endonuclease-mediated |
| Attribute String | Modified isoform(s) | Gene | Hoxb3os |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/Cas9 technology deleted the promoter region and the first exon of isoform 1. qRT-PCR indicated that isoform 1 expression was downregulated by 90%, whereas isoform 2 expression did not change in kidneys of homozygotes. No effect on the transcription of the HoxB gene cluster was seen. |
