| Primary Identifier | MGI:7595817 | Allele Type | Targeted |
| Gene | Irf6 | Transmission | Germline |
| Strain of Origin | C57BL/6NTac | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Serine codons 413 (TCC) and 424 (TCC) in exon 8 were changed to alanine (GCC) (p.S413A, p.S424A) and an FRT site flanked neomycin resistance gene cassette was inserted into intron 7. The neo cassette was removed through subsequent Flp-mediated recombination. The mutations block phosphorylation of the affected residues in the encoded peptide. |
