| Primary Identifier | MGI:7616385 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Med23 |
| Transmission | Germline | Strain of Origin | C57BL/6NTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Arginine codon 614 (CGA) in exon 16 was changed to glutamine (CAA) (p.R614Q). A loxP site, a neomycin resistance gene cassette, an FRT site flanked auto-excision protamine-cre cassette and a second loxP site were inserted into intron 16. The mutation is the equivalent of the human p.R617Q mutation associated with autosomal recessive intellectual disability 18. |
