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Allele : Med23<tm3.1Ics> mediator complex subunit 23; targeted mutation 3.1, Mouse Clinical Institute

Primary Identifier  MGI:7616390 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Med23
Transmission  Germline Strain of Origin  C57BL/6NCrl
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted into intron 3 and an FRT site flanked neomycin resistance gene cassette and second loxP site were inserted into intron 4. The neo cassette was removed through subsequent Flp-mediated recombination, leaving exon 4 floxed. Mutations in the human ortholog are associated with autosomal recessive intellectual disability 18.
  • mutations:
  • Insertion
  • synonyms:
  • Med23<tm1.1Ics>,
  • Med23<tm1.1Ics>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele