| Primary Identifier | MGI:7616475 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Tubb3 |
| Transmission | Germline | Strain of Origin | C57BL/6NTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A Cre-inducible p.M388V mutation. An FRT site flanked neomycin resistance gene cassette was inserted into an intron and subsequently removed through Flp-mediated recombination. The mutation mimics human loss-of-function mutations associated with complex cortical dysplasia with other brain malformations (CDCBM1) and congenital fibrosis of extraocular muscles 3a (CFEOM3A). |
