|  Help  |  About  |  Contact Us

Allele : Wdr62<tm1.1Ics> WD repeat domain 62; targeted mutation 1.1, Mouse Clinical Institute

Primary Identifier  MGI:7616481 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Wdr62
Transmission  Germline Strain of Origin  C57BL/6NTac
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted into intron 3 and an FRT site flanked neomycin resistance gene cassette and second loxP site were inserted into intron 7. The neo cassette was removed through subsequent Flp-mediated recombination, leaving exons 4-7 floxed. Loss-of-function mutations in the human ortholog are associated with autosomal recessive primary microcephaly 2 with or without cortical malformations.
  • mutations:
  • Insertion
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele