| Primary Identifier | MGI:7616496 | Allele Type | Targeted |
| Gene | Kif5c | Transmission | Germline |
| Strain of Origin | C57BL/6NTac | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Glutamic acid codon 237 (GAA) in exon 8 was changed to valine (GTA) (p.E237V). A loxP site, a neomycin resistance gene cassette, an FRT site flanked auto-excision protamine-cre cassette and a second loxP site were inserted into intron 8. Loss-of-function mutations in the human ortholog are associated with complex cortical dysplasia with other brain malformations 2 (CDCBM2). |
