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Allele : Phf8<tm1.1Ics> PHD finger protein 8; targeted mutation 1.1, Mouse Clinical Institute

Primary Identifier  MGI:7616499 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Phf8
Transmission  Germline Strain of Origin  C57BL/6NCrl
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted into intron 6 and an FRT site flanked neomycin resistance gene cassette and second loxP site were inserted into intron 7. The neo cassette was removed through subsequent Flp-mediated recombination, leaving exon 7 floxed. Mutations in the human ortholog are associated with Siderius X-linked mental retardation syndrome (MRXSSD).
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele