Primary Identifier | MGI:7657208 | Allele Type | Targeted |
Attribute String | Inserted expressed sequence, Null/knockout | Gene | Alb |
Inheritance Mode | Not Specified | Transmission | Germline |
Strain of Origin | C57BL/6N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Both the mouse Alb gene and the human ALB gene contain 15 exons. The mouse Alb gene sequence (approximately 10kb upstream of Exon 1 to approximately 500bp downstream of Exon 15) was replaced with the human ALB gene sequence (approximately 100kb upstream of Exon 1 to approximately 1kb downstream of Exon 15) using embryonic stem cell (ES) gene editing technology. |