Primary Identifier | MGI:7657218 | Allele Type | Endonuclease-mediated |
Attribute String | Inserted expressed sequence, Null/knockout | Gene | Calcrl |
Inheritance Mode | Not Specified | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Using gene editing technology, the sequence encoding the extracellular domain (amino acids 23 to 145) of the endogenous mouse Calcrl gene was replaced with the corresponding sequence (amino acids 23 to 146) from the human CALCRL gene, while preserving the sequence encoding the signal peptide (amino acids 1 to 22) of the mouse Calcrl gene. |