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Allele : Gt(ROSA)26Sor<em1(CAG-LOC4337827*)Ahol> gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 1, Andrew Holland
Primary Identifier  MGI:7657342 Allele Type  Endonuclease-mediated
Attribute String  Conditional ready, Epitope tag, Inserted expressed sequence Gene  Gt(ROSA)26Sor
Strain of Origin  (C57BL/6 x SJL)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  Using CRISPR/Cas9 technology, single guide RNA [5'-actccagtctttctagaaga-3'] was used to introduce a CMV-IE enhancer/chicken beta-actin/rabbit beta-globin hybrid promoter (CAG), a loxP-flanked STOP cassette including a puromycin cassette, the codon-optimized Oryza sativa F-box transport inhibitor response 1 (TIR1) sequence harboring the F74G modification and a c-myc (Myc) epitope tag, into intron 1 of the Gt(ROSA)26Sor locus on chromosome 6.
  • mutations:
  • Insertion
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Trail: Allele

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0 Mutation Involves

Phenotype

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