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Allele : Ctla4<em1(CTLA4)Cya> cytotoxic T-lymphocyte-associated protein 4; endonuclease-mediated mutation 1, Cyagen Biosciences
Primary Identifier  MGI:7657237 Allele Type  Endonuclease-mediated
Attribute String  Inserted expressed sequence, Null/knockout Gene  Ctla4
Inheritance Mode  Not Specified Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  The mouse Ctla4 gene was edited using gene editing technology to replace the sequence encoding the extracellular domain of mouse CTLA4 protein (aa.36~161) with the sequence from the human CTLA4 gene encoding the human CTLA4 protein extracellular domain (aa.36~161) while retaining the mouse signal peptide.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Ctla4<em1(hCTLA4)Cya>,
  • Ctla4<em1(hCTLA4)Cya>
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele




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