Primary Identifier | MGI:7657240 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Del(5Abcb1a-Abcb1b)2Cya |
Inheritance Mode | Not Specified | Strain of Origin | FVB/NJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Both the Abcb1a and Abcb1b genes are located on chromosome 5 and contain 28 exons. Abcb1a is located approximately 50kb upstream of Abcb1b. Using gene editing technology, the nucleotide sequence from exon 3 of the Abcb1a gene to exon 27 of the Abcb1b gene was knocked out. |