Primary Identifier | MGI:7657244 | Allele Type | Targeted |
Attribute String | Recombinase | Gene | Epx |
Inheritance Mode | Not Specified | Transmission | Germline |
Strain of Origin | C57BL/6J | Is Recombinase | true |
Is Wild Type | false |
molecularNote | The âiCre-FRT-Neo-FRT-IRES cassette was inserted upstream of the ATG start codon of the mouse Epx gene and the IRES linker was inserted to precede the exons encoding the complete Epx. Cre recombinase is expressed under the regulatory control of Epx gene elements, without impacting the endogenous expression of the Epx gene. The FRT-Neo-FRT element is used to screen positive clones during the construction process. |