| Primary Identifier | MGI:7658873 | Allele Type | Endonuclease-mediated |
| Attribute String | Hypomorph | Gene | Bmp15 |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR-targeting introduced a point mutation (c.C262T) that results in the amino acid substitution of arginine with cysteine at position 86 (R86C). This mutation results in severely reduced protein expression and corresponds to the R88C mutation observed in human patients that develop hereditary ovarian immature teratoma. |
