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Allele : Kit<em1Cya> KIT proto-oncogene receptor tyrosine kinase; endonuclease-mediated mutation 1, Cyagen Biosciences
Primary Identifier  MGI:7657288 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Kit
Inheritance Mode  Not Specified Strain of Origin  NOD.Cg-Prkdc<scid>/Cya
Is Recombinase  false Is Wild Type  false
molecularNote  The NKG-Kit*V831M mice was generated by introducing the KIT gene W41 mutation (V831M) into the background of NKG mice. Compared to NKG mice, NKG-Kit*V831M mice can undergo hematopoietic stem cell (HSC) reconstruction without irradiation, avoiding radiation-related side effects on mouse hematopoiesis, gastrointestinal tract, and nervous system.
  • mutations:
  • Single point mutation
  • synonyms:
  • Kit<em2(V831M)Cya>,
  • Kit<em2(V831M)Cya>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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