Primary Identifier | MGI:7660538 | Allele Type | Targeted |
Attribute String | No functional change | Gene | n-TUtca2 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A floxed neo-thymidine kinase cassette was inserted into the locus between the distal sequence element and proximal sequence element. RNase protection assay demonstrated that this disruption has a variable impact upon transcript levels in a tissue-ependent manner. Cre-mediated recombination removed the neomycin cassette to generate a rescue the allele. |