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Allele : Syngap1<em1Syngp> synaptic Ras GTPase activating protein 1 homolog (rat); endonuclease-mediated mutation 1, SynGAP Research Fund

Primary Identifier  MGI:7705033 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Syngap1
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  The equivalent of the human p.Q503*, C>t mutation (Q503X, nucleotide change CAG to TAG) and three upstream silent mutations (TATATGAGACTG > TACATGAGGCTC) were introduced to exon 9 of the mouse Syngap1 gene using CRISPR/Cas9 methodologies in C57BL/6J embryos.
  • mutations:
  • Nucleotide substitutions
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele