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Allele : Rr499<em1Jejo> regulatory region 499; endonuclease-mediated mutation 1, Jane E Johnson

Primary Identifier  MGI:7705091 Allele Type  Endonuclease-mediated
Attribute String  Modified regulatory region Gene  Rr499
Is Recombinase  false Is Wild Type  false
molecularNote  The Ptf1a 5' enhancer was targeted by two sgRNAs (equivalent to CACAAGTGGCGACATTCCCA and CCGCAGAGCACGCCAGTCCG) using CRISPR/Cas9 technology, resulting in an ~2.4 kb deletion containing the near and far autoregulatory PTF1-binding motifs. This allele was created in conjunction with the Rr500em1Jejo allele.
  • mutations:
  • Intergenic deletion
  • synonyms:
  • Ptf1a<AR-DNT1>,
  • Ptf1a<AR-DNT1>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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2 Publication categories

Trail: Allele