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Allele : Trim71<em1Ktka> tripartite motif-containing 71; endonuclease-mediated mutation 1, Kristopher T Kahle

Primary Identifier  MGI:7661051 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Trim71
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated an AGG to CAT change resulting in an arginine to histidine at amino acid 595 (p.R595H). This corresponds to a missense R608H mutation found in patients with hydrocephalus.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Trim71<R595H>,
  • Trim71<R595H>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele