Primary Identifier | MGI:7661051 | Allele Type | Endonuclease-mediated |
Attribute String | Humanized sequence | Gene | Trim71 |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 technology generated an AGG to CAT change resulting in an arginine to histidine at amino acid 595 (p.R595H). This corresponds to a missense R608H mutation found in patients with hydrocephalus. |