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Allele : Ogt<em1Dvaa> O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase); endonuclease-mediated mutation 1, Daan MF van Aalten
Primary Identifier  MGI:7714705 Allele Type  Endonuclease-mediated
Gene  Ogt Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated a G to A change resulting in a cysteine to tyrosine substitution at amino acid 921 (p.C921Y) in the catalytic domain. This mutation results in loss of OGT catalytic activity.
  • mutations:
  • Single point mutation
  • synonyms:
  • OGT<CDG>,
  • Ogt<C921Y>,
  • Ogt<C921Y>,
  • OGT<CDG>
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Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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