Primary Identifier | MGI:7714930 | Allele Type | Endonuclease-mediated |
Attribute String | Modified regulatory region | Gene | Rr544 |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The Taar cluster enhancer, located between Taar1 and Taar2, was targeted using sgRNAs with CRISPR/Cas9 technology, resulting in a 996 bp deletion (GRCm39:chr10:23,806,230-23,807,225). The allele was created in zygotes heterozygous for the Taar1tm1Tboz and Taar4tm1.1Tboz alleles. The allele was created in conjunction with the Rr545em2Tboz allele and Taar4tm1.1Tboz Rr544em2Tboz Rr545em2Tboz mice were selected for experiments. |